Blocking ion channel improves muscle function, survival in mice with severe DMD
September 13, 2022 -- Researchers at Johns Hopkins Medicine have discovered that blocking an ion channel increases muscle function and survival in mice with severe Duchenne muscular dystrophy (DMD), a genetic disorder that progressively weakens skeletal and heart muscles over time. Read More
Biden appoints Ginkgo Bioworks’ Renee Wegrzyn as 1st director of ARPA-H
September 13, 2022 -- President Joe Biden on Monday appointed biologist and former government scientist Renee Wegrzyn, PhD, as the inaugural director of the new Advanced Research Projects Agency for Health (ARPA-H). Read More
Researchers discover what causes cancer cells to eat proteins
September 13, 2022 -- European researchers have identified the molecular pathway that allows cancer cells to start breaking down surrounding proteins as a food source when facing starvation. The discovery has implications for cancer research and treatment. Read More
NIH researchers develop gene therapy for rare pediatric disease that causes blindness
September 9, 2022 -- Using patient-derived retinal organoids, researchers from the National Institutes of Health (NIH) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood. Read More
Women researchers in life sciences face gender inequities in mentoring
September 9, 2022 -- There is a disproportionate tendency for women to leave academic research instead of advancing to positions in which they become mentors themselves, according to an analysis of formal PhD and postdoctoral mentoring relationships in the life sciences. Read More
Link between ion channel and cholesterol in brain may lead to novel treatments for Alzheimer’s
September 8, 2022 -- Mechanical forces and tissue functions influence the morphology of the developing brain, according to University of California, Irvine researchers, who also discovered a direct link in neural stem cells between Piezo1 -- a mechanically-activated ion channel -- and intracellular cholesterol levels during neural development. Read More
Antibody reduces amyloid pathology in mice with Alzheimer’s disease
September 7, 2022 -- Researchers from the University of Texas Health Science Center at Houston have shown that a newly developed agonistic antibody has therapeutic effects in mice with Alzheimer’s disease. Read More
Scientists discover how cells repair damaged lysosomes, offers better understanding of age-related diseases
September 7, 2022 -- University of Pittsburgh researchers have described for the first time a pathway by which cells repair damaged lysosomes, structures that contribute to longevity, offering the potential to better understand and treat age-related diseases. Read More
HHMI researchers spot new synapse in primary cilia of neurons
September 6, 2022 -- There’s a new kind of synapse in the primary cilia of neurons, according to researchers at Howard Hughes Medical Institute’s (HHMI) Janelia Research Campus in Ashburn, VA. Read More
St. Jude team unlocks mystery of persister cells
September 6, 2022 -- A team from St. Jude Children’s Research Hospital has discovered the specific cause for why certain cells don’t undergo apoptosis and instead create a new generation of “persister cells," according to an article published September 1 in the journal Cell. Read More
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