Researchers identify diabetes-causing mechanism in mice
November 8, 2022 -- Osaka University researchers have identified a mechanism in which a lack of insulin is reported back to insulin-producing pancreatic cells. The research on mice, published on November 7 in the journal iScience, identifies potential new targets for diabetes therapy. Read More
Sex differences impact neurodegeneration
November 7, 2022 -- For neurodegenerative diseases, one size does not fit all, and that’s why UCLA researchers have emphasized the importance of taking sex differences into account in a new study. The effect of certain X chromosome genes in females (XX) compared with males (XY) can be assessed for their role in neurodegeneration during aging, thus offering a roadmap for clinicians in treating these diseases. Read More
Scientists identify infectious monkeypox virus mutations
November 7, 2022 -- University of Missouri researchers have identified the specific mutations in the monkeypox virus that make it so infectious. The results could lead to modified versions of existing drugs or the development of new ones. Read More
Influenza replication structure revealed, making way for new antivirals
November 7, 2022 -- Collaborative research between the University of Oxford and Diamond Light Source has revealed detailed influenza replication structures. The study, published November 3 in the journal Trends in Microbiology, furthers understanding of the virus’ adaptation to different hosts, and may lead to new antiviral drugs. Read More
Scientists prevent resistance in protein 'degrader' cancer therapy
November 4, 2022 -- The latest oncology drugs target and degrade harmful pathogenic proteins. However, researchers have identified resistance mechanisms to this treatment and how to overcome them. Read More
Researchers develop novel platform to improve immunotherapy
November 4, 2022 -- Researchers have discovered a novel pathway very early during in vitro differentiation that supports the emergence of T cells and natural killer cells from human induced pluripotent stem cells. Read More
Autism affects the brain writ large: study
November 3, 2022 -- Autism affects not only the portions of the brain related to social behavior and language but also the cerebral cortex, a new University of California, Los Angeles study finds. Read More
Nutritional supplement offers potential treatment for Feingold syndrome
November 3, 2022 -- Reduced protein synthesis in developing gut cells contributes to the rare genetic intestinal disorder Feingold syndrome type 1, but a nutritional supplement may help reverse it. Read More
Scientists advance understanding of metastasis, cancer cells exposed to high viscosity
November 2, 2022 -- An international team of scientists has discovered how cancer cells exposed to high viscosity environments change the way they move to improve their invasiveness and favor metastases. Read More
Treatment target for sleep apnea found in obese mice
November 1, 2022 -- In a new study on obese mice, Johns Hopkins Medicine researchers have found that specialized channel proteins are possible therapeutic targets for sleep apnea. Read More
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