Researchers study how latent HIV evades antiretrovirals and immunity
November 15, 2022 -- Duke University researchers have discovered that an immune response meant to help fight infections is the likely mechanism that drives human immunodeficiency virus (HIV) into latency, lurking in cells until it erupts anew. Read More
NCI $5.7M grant funds cancer vaccine research
November 14, 2022 -- The National Cancer Institute (NCI) has awarded a five-year, $5.7 million grant to a team of Weill Cornell Medicine researchers to fund the development of mRNA vaccines to prevent cancer in high-risk populations. Read More
Mast cells in women may explain osteoarthritis pain differences between sexes
November 14, 2022 -- Researchers from the Hospital for Special Surgery have found that an increased level of immune cells -- called mast cells -- in synovial tissue surrounding the knee joint in women may help explain why women with knee osteoarthritis report worse pain than men. Read More
Immune conversion of cancer cells sensitizes them to immunotherapy
November 14, 2022 -- Researchers at the University of Texas MD Anderson Cancer Center have developed a nanotechnology platform that changes the immune system's perception of solid tumor cells, making them more receptive to immunotherapy. Read More
X chromosome turned off in male cancers too
November 10, 2022 -- Some male cancers of diverse subtypes activate the gene responsible for shutting down gene expression of the X chromosome, Xist, and display features of X inactivation, according to researchers at the Dana-Farber Cancer Institute in Boston. Read More
Dopamine ‘brake’ discovery may help treat Parkinson’s disease
November 9, 2022 -- Researchers from Oregon Health & Science University have revealed that the neurotransmitter adenosine puts the brakes on dopamine in the brain, potentially facilitating new Parkinson’s disease treatments. Read More
New radiopharmaceutical treatment targets prostate cancer
November 9, 2022 -- Osaka University and Dusseldorf University researchers have found that a new radiopharmaceutical treatment targeting prostate-specific membrane antigen -- a protein expressed on prostate cancer cell surfaces -- can zero in on tumor cells with precision. Read More
Key protein may help predict lung cancer patient survival: study
November 9, 2022 -- A team, led by researchers from the University of Edinburgh, has studied the role of the protein toll-like receptor 2 (TLR2) as a key tumor suppressor. Their findings, published November 8 in the journal Cell Reports, could aid in early detection of lung cancer. Read More
New insights on how HIV-1 evades the immune system
November 8, 2022 -- Université de Montréal researchers found that the type of virus used as a model significantly impacted the efficacy of non-neutralizing antibodies against the AIDS virus in mice. Read More
Sugar molecules targeted in cancer therapy
November 8, 2022 -- University of Basel researchers have discovered a way to neutralize cancer cells' use of sugar molecules to disable attacks by the body's immune system. The study, published on November 2 in the journal Science Translational Medicine, may provide a new immunotherapy target. Read More
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