Applied Biomath highlights presentations at SITC meeting

By The Science Advisory Board staff writers

November 4, 2021 -- Applied Biomath is highlighting two poster presentations being offered at the upcoming Society for Immunotherapy of Cancer (SITC) meeting in Washington, DC.

Company principal scientist David Flowers, PhD, will present a poster titled, "A Computational Semimechanistic Pharmacology Model of ATG-101, a PD-L1/4-1BB Bispecific Antibody for Treatment of Solid Tumors." The work describes the company's collaboration with Antengene on the development of a systems pharmacology model for understanding the treatment's tumor-killing mechanism.

A second poster presentation describes results of the company's collaboration with Genmab and is titled, "Dose Selection for DuoBody-PD-L1×4-1BB (GEN1046) Using a Semimechanistic Pharmacokinetics/Pharmacodynamics Model That Leverages Preclinical and Clinical Data."

The SITC meeting will be held November 10-14, 2021.

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