Scientists uncover DNA repair mechanism, potential cancer target
Scientists from the Francis Crick Institute and biotech company Artios have revealed how polymerase theta, a DNA repair enzyme, becomes vital to certain cancers' survival when those cancer cells are unable to use a more common DNA repair method. Read More
Gene mutation may explain Alzheimer's brain plaque buildup
Researchers at the New York University Grossman School of Medicine and the Icahn School of Medicine at Mount Sinai have found that a gene mutation may prevent brain cells from clearing away plaque -- protein filled clumps that build up in the brain and are characteristic of Alzheimer's disease. Read More
Researchers discover new form of undetectable antimicrobial resistance
Australian researchers have discovered a new form of antimicrobial resistance that is undetectable using traditional testing methods. Their findings may help in the development of future antibiotics to tackle new mechanisms of antibiotic resistance. Read More
Scientists highlight new insights into triple-negative breast cancer
Boston University researchers have demonstrated that control of a certain cellular pathway can prevent the development of triple-negative breast cancer, which they contend could help identify new therapeutic options. Read More
Increasing immune cell production may reverse cognitive decline: study
Rutgers University researchers have discovered that the underproduction of immune cells called mucosal-associated invariant T cells contribute to Alzheimer’s disease and other cognitive disorders. Their study, published November 21 in the journal Nature Immunology, shows how increasing these cells could reverse the damage. Read More
Rogue killer T cells contribute to autoimmunity: study
Scientists from the Garvan Institute of Medical Research have found new insight into the role that killer T cells play in leukemia and autoimmune disease. They contend that their findings could be helpful in narrowing down pathways to target these cells for future treatments. Read More
Computerized approach may boost drug discovery
University of Texas at Dallas and Novartis Pharmaceuticals researchers have created a computer-based platform that could make the currently lengthy and expensive drug discovery process more effective, more efficient, and less costly. Read More
Novel nanoparticles deliver cancer therapy
University of Pittsburgh researchers have designed cancer-fighting nanoparticles that co-deliver an existing chemotherapy drug along with a novel immunotherapy that silences an immunosuppression gene. Read More
Tankyrase holds potential for bowel cancer drug development: study
Scientists from the Institute of Cancer Research, London have discovered the inner workings of a protein called tankyrase, which plays a key role in driving bowel cancer. The researchers contend that their findings could open the door for better and less toxic cancer drugs. Read More
CRISPR-based tool cuts and pastes genes where needed
Massachusetts Institute of Technology researchers have designed a new CRISPR-based tool that can snip out faulty DNA sequences and safely replace them with new ones at desired cell sites. Read More
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