Cell and gene therapy sector is in midst of an ‘industrial revolution’: Miguel Forte

About five or six years ago, the biotechnology and pharmaceutical industries “woke up to strong clinical data” in the cell and gene therapy sector leading to “industrial capabilities” delivering products, contends Dr. Miguel Forte, PhD, CEO of Bone Therapeutics and president-elect of the International Society for Cell & Gene Therapy (ISCT).

Forte believes the cell and gene therapy market is in midst of an "industrial revolution" thanks to a "clinical revolution" that preceded it a few years ago with "well-documented data" that demonstrated these technologies were "bringing value to patients" with "unprecedented" results on some very difficult medical indications.

"The biggest challenge was to make sure that we could produce sufficient products in a cost-effective, reproducible, and consistent manner," Forte said. "CDMOs, enablers, technology -- all that started to grow and now we're seeing enormous developments of those industrial capabilities of delivering products."

Science Advisory Board spoke with Forte at last week's 2022 Cell & Gene Meeting on the Mesa in Carlsbad, CA, organized by the Alliance for Regenerative Medicine (ARM), where it was announced that he had been elected to ARM's 2023 Executive Committee and Board of Directors. Forte sees ARM and ISCT as complementary organizations.

"It's important in a field like cell and gene therapy that we not only do our day job -- in my case CEO of Bone Therapeutics -- but we participate in the field because all together we need to move the dial" by collaborating with regulators, providers, and companies, Forte said.

ARM and ISCT "are particularly good for that" but they come at it from different perspectives, according to Forte. He pointed out that ARM "has got a very intense focus on lobbying" from a company perspective -- among other activities -- and while ISCT "shares those interests" that organization "tackles it more from a translational perspective bridging the work between academics, where a lot of ideas are generated, and industry where those ideas become products and reach the patients."

Watch this video to learn more.

Manufacturing remains big challenge for cell and gene therapy industry
Science Advisory Board spoke with Eric Blair, chief commercial officer for Andelyn Biosciences, at last week’s 2022 Cell & Gene Meeting on the...
Roadblocks continue to hamper CGT companies as they look to commercialize their products
The cell and gene therapy (CGT) sector will continue to face investment and regulator challenges in the near term. That’s the consensus of companies in...
FDA biologics chief outlines ways to remove barriers to cell and gene therapies
At this year's Meeting on the Mesa, the U.S. Food and Drug Administration’s top biologics regulator said the use of a “cookbook” for developing cell and...
ISCT22: Cell therapy has potential to address unmet medical needs in orthopedics
Miguel Forte, CEO of Bone Therapeutics, and president-elect of the International Society for Cell & Gene Therapy (ISCT), spoke with ScienceBoard.net...

Copyright © 2022 scienceboard.net

Last Updated 10/18/2022 2:02:53 PM