UCB, Roche to develop antibodies for Alzheimer's disease

By The Science Advisory Board staff writers

July 29, 2020 -- Biopharmaceutical firm UCB has signed a deal to provide Roche and Genentech with an exclusive, worldwide license to its UCB0107 antitau antibody treatment for people living with Alzheimer's disease.

In addition to receiving an initial upfront payment of $120 million, UCB will also receive, after positive completion of a proof-of-concept study in Alzheimer's disease, further payments with a total potential consideration approaching $2 billion upon receipt of certain regulatory approvals and satisfying certain milestones, according to the vendor.

UCB noted that it will fund and perform the initial proof-of-concept study for the investigational monoclonal antibody drug in Alzheimer's disease. Once the study has been completed and results are available, Genentech will then have the right to proceed with clinical development or return full rights back to UCB, the company said.

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