ElevateBio, University of Pittsburgh awarded $100M grant to create biomanufacturing center
August 26, 2022 -- ElevateBio and the University of Pittsburgh have been awarded a $100 million grant from the Richard King Mellon Foundation to create the Pitt BioForge BioManufacturing Center at Hazelwood Green in Pittsburgh. Read More
Nonviral CRISPR approach simplifies reengineering of large quantities of cells for therapeutics
August 25, 2022 -- Scientists at the Gladstone Institutes and the University of California, San Francisco have developed a new approach using CRISPR-Cas9 gene editing to produce massive quantities of cells for therapeutic applications. Read More
Gensaic, Ovid Therapeutics partner on phage-derived gene therapies for CNS
August 25, 2022 -- Gensaic is collaborating with Ovid Therapeutics to develop up to three genetic medicines for central nervous system (CNS) disorders using its proprietary phage-derived particle platform. Read More
Roche launches its first digital PCR for cancer, other diseases
August 24, 2022 -- Diagnostics company Roche has launched its first digital polymerase chain reaction (PCR) system, designed to accurately quantify trace amounts of specific DNA and RNA targets not typically detectable by traditional PCR technology. Read More
Biologists provide insights on genetic parasites and their links to disease
August 24, 2022 -- University of California, Irvine biologists have shed light on the complex mechanisms of transposons, genetic parasites that comprise over half of the human genome, which selfishly make proteins solely to copy their own DNA. Read More
Common molecular tool for DNA labeling has surprising anticancer properties
August 23, 2022 -- Scientists at the University of North Carolina School of Medicine have discovered that a molecule called EdU (5-ethynyl-2'-deoxyuridine), a common molecular tool for DNA labeling, has surprising anticancer properties that warrant further investigation. Read More
Animal studies provide new insights into mechanisms behind Crohn’s disease
August 22, 2022 -- Researchers, led by Massachusetts General Hospital, have found that inhibitors of an enzyme called Speckled Protein 140 can reverse intestinal abnormalities in mice with inflammation characteristic of Crohn's disease. Read More
NSF awards $6M to develop purification membranes for large-scale manufacturing of viral vectors
August 19, 2022 -- The National Science Foundation (NSF) has awarded a $6 million grant to researchers at the University of Arkansas and two partner institutions to develop purification membranes for future large-scale manufacturing of viral vectors and viruslike particles. Read More
Innovative approach keeps cells alive during RNA extraction
August 17, 2022 -- Scientists at the Swiss Federal Institute of Technology Lausanne (EPFL) and ETH Zurich have jointly developed an innovative single-cell transcriptome profiling approach, called Live-seq, that keeps cells alive during RNA extraction for further study while also being minimally invasive. Read More
New technology reveals how environmental changes affect RNA structure in living cells
August 17, 2022 -- Researchers at the John Innes Centre in the U.K. have developed a new technology that is capable of profiling RNA structure at the resolution of a single molecule in live cells. Read More
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