Novocellbio's COVID-19 cell therapy shows promising results

By The Science Advisory Board staff writers

August 10, 2020 -- Novocellbio has confirmed that its autologous natural killer (NK) cell treatment agent Novo-NK is effective in killing SARS-CoV-2.

The therapy is developed from NK cells, which are rapidly deployed natural immune cells that detect cancer, viruses, and bacteria. The Novo-NK therapy is derived from isolates of NK cells from a small amount of a patient's blood.

In the experiment, monkey kidney cells (Vero E6) infected with SARS-CoV-2 were treated with Novo-NK cells. The analysis showed that the therapy successfully decreased the virus's effects in various controlled time periods and effectively killed the virus within six hours. The treatment has also been shown to increase immunity by reducing the risk of reinfection from virus or cancer cell mutation.

Novocellbio is conducting further preclinical studies to understand the mechanism of Novo-NK therapy against SARS-CoV-2. The company is also preparing for a phase I clinical trial of Novo-NK for the treatment of lung cancer based on successful results in preclinical animal models.

Celularity begins trial of COVID-19 cell therapy
Celularity has received funding to support a phase I/II clinical trial of human placental hematopoietic stem cell-derived natural killer cells for the...
Therapeutic Solutions to use immunotherapy for COVID-19
Therapeutic Solutions plans to develop its clinical stage cancer immunotherapy treatment StemVacs for treatment of COVID-19 patients.
Avectas, ONK to develop cancer cell therapy
Avectas has exclusively licensed a chimeric antigen receptor-directed natural killer cell therapy from ONK Therapeutics for the treatment of B-cell malignancies...
Kleo, Green Cross collaborate on COVID-19 NK combination therapy
Kleo Pharmaceuticals is joining forces with Green Cross LabCell of South Korea to advance testing of natural killer (NK) cell therapies as a potential...

Copyright © 2020 scienceboard.net


Register below for our weekly Letter from the Editor to receive the latest Science news and insights.
Email
Conferences
ESMO Virtual Congress 2020
September 14-29
Online
2020 ACCP Annual Meeting
September 20-22
Online
BioProcess International West
September 21-25
Online
BioProcess International
September 21-25
Online
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter