Researchers used Kernel's Flow headset to measure cortical hemodynamics in research subjects given ketamine, which gave individuals an altered state of consciousness. The technology measured the neuroeffect of the drug and confirmed changes in functional connectivity that are consistent with current scientific research, according to the results.

(Top) Absolute functional connectivity in a research subject for minutes five to 15 after he received the 57.75-mg intramuscular injection of ketamine. (Bottom) Subject's relative functional connectivity changes after the Ketamine took effect starting at minutes 15 to 25. Images courtesy of Kernel.

For the pilot study, participants received either a low dose of ketamine and/or a placebo while wearing the Flow headset, which is equipped with sensors to record brain activity. Participants' experiences are being reported using structured questionnaires and validated assessments during study visits and at follow-up.