Bruker unveils various new instruments, software at Analytica 2022

By The Science Advisory Board staff writers

June 27, 2022 -- Bruker launched various scientific instruments, software, and other products at Analytica 2022, which took place June 21-24 in Munich.

The new Hyperion II FT-IR/IR laser imaging microscope combines Fourier transform infrared (FTIR) microscopy with quantum cascade laser (QCL) infrared (IR) laser imaging to provide all three transmission, reflection, and attenuated total reflectance (ATR) modes. The microscope has an imaging speed of 6 mm² per second.

The thermogravimetric analysis (TGA) II FT-IR module enables gas analysis by hyphenation of thermogravimetry (TG) and FTIR spectroscopy. The cell design allows high-temperature analysis up to 370° C. Also, most applications can be covered with a deuterated triglycine sulfate (DTGS) detector without the need for liquid nitrogen, the firm said.

Bruker also introduced a point-of-need mass spectrometry (MS) for accelerated measurements without chromatography that is suitable for food, beverage, forensics, industrial, security, environmental, and pharmaceutical applications. The Dart-Evoq triple quadrupole MS system was developed with the IonSense Dart source to reduce analysis time with little to no preparation for analyses of solid, liquid, or gas samples.

The firm also highlighted its new Fourier 80 system, a high-performance 80 MHz Fourier Transform nuclear magnetic resonance (FT-NMR) benchtop spectrometer with capabilities for pharmaceutical and chemical analysis. The Fourier 80 has 1H sensitivity of 200:1 for gradient spectroscopy proton probes and an adjustable temperature option allowing analysis up to 60° C, which is compatible with the Fourier 80 PAL sample changer option.

The new benchtop FT-NMR Reaction Monitoring product and GxP Readiness Kit for the Fourier 80 reaction monitoring solution RxnLab is another new product that features temperature-controlled reaction paths for process control and monitoring reaction products with the new Fourier 80 flow accessory. Using InsightMR software, the RxnLab brings benchtop FT-NMR to bio and chemical production for non-NMR experts. The product also integrates the trapped ion mobility spectrometry time-of-flight (timsTOF) flex platform with 5 µm single-cell resolution and novel matrix-assisted laser desorption/ionization (MALDI HiPLEX-IHC) assays.

Bruker's NeuraLight 3D Ultra module expands neuroscience research capabilities and optogenetics applications using Bruker's Ultima multiphoton microscopes. The 3D system provides 3D holographic photostimulation to study neural networks and brain computation. It builds upon spatial light modulator (SLM) technology to use a new, larger liquid crystal chip for a larger field of view, improved targeting precision, and a speed of 600 hologram frames per second.

The firm also introduced XFlash 7, a next generation of energy dispersive x-ray detector for elemental analysis with Quantax energy dispersive x-ray spectrometer (EDS) accessories. The product enables chemical analysis on electron microscopes with speed, sensitivity, and reliability, Bruker said. The detectors come in a range of sizes, shapes, and window materials that are designed to provide maximum collection angles for x-rays and an optimized ratio of active detector area and sample-detector distance.

Lastly, the new timsTOF high-throughput (HT) features a 4th-generation TIMS-XR cell and 14-bit digitizer for more range in proteomics, enhanced peptide coverage, and more accurate quantitation, particularly in 4D plasma and tissue proteomics and epiproteomics. The dia- parallel accumulation-serial fragmentation (PASEF) acquisition on the timsTOF HT quantifies proteins across a large range even in difficult samples, such as cardiac tissue, without sacrificing throughput or sensitivity, Bruker said.

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