The research aimed to understand the development and maturation of biofilms to better understand their resistance to the innate immune system. Researchers found that Z-form extracellular DNA (eDNA) is a structural component of the bacterial biofilm matrix (Cell, November 3, 2021).

The company said these findings suggest that the development of therapeutic agents designed to drive biofilm eDNA back into its native B form could prevent or resolve biofilm-mediated diseases.