NIH researchers isolate effective COVID-19 nanobody

By The Science Advisory Board staff writers

December 22, 2020 -- It is possible to treat COVID-19 successfully using nanobodies -- tiny antibodies -- derived from llamas, and one effective nanobody has been identified, researchers affiliated with the U.S. National Institutes of Health (NIH) reported in Scientific Reports online December 22.

Experience with nanobodies taken from a llama named Cormac suggest the potential to prevent infections and prevent the transmission of the virus, Dr. David Brody, PhD, director of the Center for Neuroscience and Regenerative Medicine at the Uniformed Services University of the Health Sciences in Bethesda, Md, reported.

One nanobody, dubbed as NIH-CoVnb-112, worked in liquid and aerosol forms and was effective after inhalation, researchers reported. Low levels of the NIH-CoVnb-112 nanobodies prevented infection in in vitro studies, they reported.

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