October 6, 2020 -- Unchained Labs has launched a new gene therapy quantification application on Stunner, its gene therapy platform.
Stunner's new adeno-associated virus (AAV) application provides researchers with a full readout of how many AAV capsids they have, how many capsids are packed with DNA, and if there is any aggregation. This can be achieved in less than one minute and with only 2 µL of sample.
Stunner pulls together ultraviolet-visible concentration from the sample and measures the total protein and DNA in it. Dynamic light scattering identifies AAV capsids based on their size and checks for aggregation. Stunner then combines all the information measured to provide an accurate titer and empty/full ratio.