Zymeworks, Merck to develop multispecific antibodies

By The Science Advisory Board staff writers

July 9, 2020 -- Merck has signed a research and licensing agreement to develop multispecific antibody therapeutic candidates using platforms from clinical-stage biopharmaceutical company Zymeworks.

Under terms of the agreement, Merck has provided Zymeworks with an undisclosed upfront payment. In return, Zymeworks will provide Merck with a worldwide, royalty-bearing license to research, develop, and commercialize as many as three multispecific antibodies.

Should the programs create an approved product, Zymeworks is eligible to receive up to $411 million in option exercise fees and clinical development and regulatory approval milestone payments. The company can also receive up to $480 million in commercial milestone payments and tiered royalties on sales.

Merck and Zymeworks have previously partnered to develop bispecific antibodies, including instituting an expanded partnership in 2014. The new agreement does not impact the original partnership, the companies noted.

Merck to acquire Themis for SARS-CoV-2 vaccine
Merck announced on May 26 that it has entered an agreement to acquire privately held Themis, a company that is developing a vaccine candidate for SARS-CoV-2.
Merck, Ridgeback Bio partner on COVID-19 antiviral
Merck and Ridgeback Biotherapeutics announced that they have entered a collaboration to develop EIDD-2801, an orally available antiviral candidate in...
IAVI, Merck partner on SARS-CoV-2 vaccine
Merck and IAVI, a nonprofit scientific research organization, announced that they are partnering to develop a recombinant vesicular stomatitis virus vaccine...
Serimmune, Merck reach drug discovery milestone
Serimmune has used its immune mapping technology on clinical and preclinical samples provided by Merck.
Merck to build new biotech R&D center in Switzerland
Merck announced on January 27 an investment of 250 million euros ($275 million) to build a new biotech R&D center in Corsier-sur-Vevey, Switzerland.

Copyright © 2020 scienceboard.net


Conferences
Cell Bio 2021
December 11-15
San Diego, California United States
Antibody Engineering and Therapeutics
December 13-17
San Diego, California United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter