Merck to acquire Pandion for $1.85B

By The Science Advisory Board staff writers

February 25, 2021 -- Merck has announced that it will acquire Pandion Therapeutics for $1.85 billion.

The deal will boost Merck's ability to further develop a range of drug candidates for autoimmune diseases, it said. It will make the purchase through one of its subsidiaries.

Pandion is developing immune modulators that target immune system control nodes, according to Merck. The company's lead candidate is PT101, an engineered interleukin-2 (IL-2) mutein (protein with an altered amino acid sequence) fused to a protein backbone that activates regulatory T cells for the treatment of autoimmune diseases; Pandion has completed a phase IA clinical trial for the drug.

Pandion's pipeline also includes programmed cell death 1 (PD-1) agonists in development for several autoimmune diseases.

The transaction is expected to close in the first half of this year.

Starpharma, Merck collaborate on new ADCs
Starpharma has signed a research agreement with Merck to conduct preclinical research on dendrimer-based antibody-drug conjugates (ADCs) utilizing Starpharma's...
Artiva, Merck to develop CAR NK cell therapies
Artiva Biotherapeutics and Merck have signed an agreement to develop chimeric antigen receptor (CAR) natural killer (NK) cell therapeutics for solid tumors.
Merck discontinues work on COVID-19 vaccines to focus on therapeutics
Merck will discontinue development of its COVID-19 vaccine candidates because they produced a lower immune response compared to natural infection or other...
Janux, Merck partner on T-cell engager immunotherapies
Janux Therapeutics has entered into a strategic collaboration and licensing agreement with Merck to discover, develop, and commercialize next-generation...
Merck KGaA, Artios partner on DNA damage response drugs
Artios Pharma and Merck KGaA are set to develop multiple cancer drugs aimed at DNA damage response pathways through a new three-year long research and...

Copyright © 2021

Microscopy and Microanalysis Meeting
July 31 - August 4
Portland, Oregon United States
Glasgow International Health Festival
August 24-27
Glasgow, Glasgow City United Kingdom
Pharma Competitive Intelligence Conference and Exhibition
September 21-22
Newark, New Jersey United States
BioProcess International (BPI) Conference
September 27-30
Boston, Massachusetts United States
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter