Allen Institute extends cell line contract

By The Science Advisory Board staff writers

February 3, 2020 -- The Allen Institute for Cell Science announced on February 3 that it has extended its contract with the Coriell Institute for Medical Research for the storage and distribution of its Allen Cell Collection. Since its launch in 2016, the collection has grown from five cell lines to more than 40 lines today. The new agreement between the institutes will extend for an additional three years.

The collection is composed of gene-edited human induced pluripotent stem cell lines developed using CRISPR/Cas9 technology. The collection is ideal for live cell imaging to capture organelle dynamics and function in normal and disease models. Across the cell lines, 33 unique cellular structures have been tagged. With dual- and triple-edited cell lines, several key structures can be highlighted within the same cell.

With this extension, the Allen Institute will make the collection available to academic researchers and commercial entities.

The Coriell Institute for Medical Research will hold the cell lines in their biobanks. They will provide services in pipeline development with an emphasis on quality control and assessing the genomic, structural, and pluripotency integrity of cells.

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