COVID data repository helps track pandemic in SF hospitals
ORLANDO -- Consistent persistence in the face of chaos is how San Francisco Department of Public Health Chief Information Officer Eric Raffin and his team implemented their COVID-19 hospitalization data repository. Raffin shared his experience during a Tuesday session at the 2022 Healthcare Information and Management Systems Society meeting. Read More
'Roadmap' reveals how cells transform during mouse embryonic development
Mapping how complex animals develop from a single cell is a key area of study, but it remains a significant challenge. Now, research published in Nature Genetics on March 14, has laid out the molecular changes that control how cells transform during mouse embryonic development. The resulting roadmap identifies potential links between cell types to help understand the paths they take toward specialization. Read More
11 new developments in cell and gene therapy
There have been a number of recent developments in the cell and gene therapy field. Bruce Carlson, publisher of Cell and Gene Therapy Business Outlook, offers a look at the 11 biggest developments. Read More
AI-designed protein can awaken silenced genes
Scientists have shown that it is possible to regulate dormant genes by combining CRISPR technology with a protein designed with artificial intelligence (AI). The finding, published recently in Cell Reports, has the potential to be an epigenetic tool in biomedical research and used as a therapeutic approach for a wide range of diseases. Read More
New checkpoint target boosts immunotherapies against solid tumors in mice
The human immune system can be a powerful weapon in halting the spread of cancer, leading to long-term remission. However, many tumors find ways to protect themselves by switching off the immune response. Scientists have discovered a new way to reactivate T cells to attack solid tumors and boost existing therapies in mice, according to research published in Cancer Discovery on March 8. Read More
Researchers grow functional pancreatic beta cells from stem cells
A research group has demonstrated that stem cells can form cells that closely mimic normal pancreatic islets, in terms of both structure and function. The findings, which were published in Nature Biotechnology on March 3, show how stem cell islets can be used as tools for diabetes research and cell therapies. Read More
Targovax and Agenus team up on mutant KRAS cancer vaccine
Targovax and Agenus have entered into a clinical collaboration and supply agreement to combine Targovax's TG mutant KRAS cancer vaccines with Agenus' clinically validated and U.S. Food and Drug Administration-approved QS-21 Stimulon adjuvant. Read More
How diversity, inclusion help one company turn sci-fi into sci-fact
Juliana Blum, PhD, co-founder and executive vice president of corporate development at Humacyte, spoke with ScienceBoard about diversity and inclusion in the life sciences, especially about being a woman in science. Read More
Combined imaging approach gives detailed picture of blood vessels
Mapping out the intricate network of blood vessels in tissues can help researchers to better understand the changes in diseases like dementia or cancer. However, techniques to image the vasculature are individually limited and difficult to combine. Now, a new easy-to-use system, described in a paper published February 10 in the journal Nature Methods, can combine multiple imaging techniques to provide more detailed information at a range of scales. Read More
Experience sharing is critical for women in science
Sharing experiences with future generations is key to moving science and biotechnology forward. As a female leader of a biotechnology company, Dr. Bridget Martell, CEO of Artizan Biosciences, shares her experiences and perspectives with ScienceBoard. Read More
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