Research shows heart-damaging route of SARS-CoV-2 spike protein
Researchers have demonstrated that the spike protein from the SARS-CoV-2 virus can lead to heart muscle injury through the inflammation process, according to preliminary research to be presented this week at the American Heart Association’s 2022 Basic Cardiovascular Sciences Scientific Sessions. Read More
Scientists discover biomarkers associated with acute, chronic phases of TBI
Arizona State University scientists have provided some of the first detailed view of the molecular and cellular mechanisms behind traumatic brain injury (TBI) as the condition progresses from the acute to the chronic phase. Read More
Analysis of nanoparticles, cancer cells could aid development of nanoparticle-based drugs
Researchers have identified biomarkers that predict whether different types of cancer cells will take up specific nanoparticles, potentially helping to overcome some obstacles to the development of nanoparticle-based drugs. Read More
Lessons from Operation Warp Speed could benefit future drug discovery
What lessons can the biotech industry learn from Operation Warp Speed? In an interview with ScienceBoard.net, Debrah Thompson, PhD, of HTG Molecular Diagnostics, discusses how the success of the COVID-19 vaccine rollout could benefit the drug discovery process going forward. Read More
New DNA editing tool could enable more personalized cell therapies
University of Minnesota, Twin Cities researchers have developed a new tool to predict and customize the rate of a type of DNA editing called site-specific recombination, offering the potential for more personalized cell therapies. Read More
Repetitive DNA linked to cancer formation in study of replication process
Researchers have discovered that noncoding "junk" DNA could potentially contribute to the development of cancer. Repetitive DNA sequences can cause replication to stall, triggering a response that is similar to the one induced by DNA damage, according to a study published July 19 in Nature Communications. Read More
Current COVID-19 boosters provide protections against serious infection: study
Despite the evolution of the SARS-CoV-2 pandemic coronavirus, a new laboratory study conducted by a team of international researchers suggests current vaccine boosters may elicit sufficient immune protection against severe omicron-induced COVID-19 disease. Read More
Loss of protective protein linked to age-related changes in the eye
A study in mice has shown that the loss of a protein that protects retinal support cells may drive aging-associated diseases of the retina such as macular degeneration. Read More
Study shows potential of CRISPR-Cas9 tools for synthetic gene control, cellular engineering
Rice University researchers were able to use deactivated Cas9 (dCas9) proteins to target key segments of the human genome to synthetically trigger the transcription of human genes. Using dCas9 proteins, researchers have revealed important details about human promoters and enhancers. Read More
Single-cell analyses shed light on drug resistance of melanoma brain metastases
Using single-cell genetic analyses of frozen brain samples, Columbia University researchers have uncovered evidence of how melanoma brain metastases evade current treatments. Read More
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