Cell therapy startup NKILT Therapeutics takes novel approach to targeting leukemia
Biotech startup NKILT Therapeutics is developing a novel approach of engineering natural killer cells to directly target leukemias and solid tumors. Science Advisory Board spoke with Raphaël Ognar, co-founder and CEO of the company earlier this month at the 2022 Cell & Gene Meeting on the Mesa in Carlsbad, CA. Read More
Identification of genetic drivers of radiotherapy sensitivity opens door to treatment optimization
Using in silico and experimental profiling platforms, researchers at Northwestern Medicine have identified genetic biomarkers of radiation sensitivity, pointing to opportunities to use genomics to guide radiotherapy treatment for cancer patients. Read More
Antion Biosciences takes allogeneic approach to therapies with microRNA technology
Science Advisory Board spoke with Dr. Sven Kili, CEO of Antion Biosciences, at last week’s 2022 Cell & Gene Meeting on the Mesa, where he laid out his vision for where the company is heading and what the industry needs to do to cure diseases with significant unmet medical needs. Read More
CRISPR interference screening reveals mitochondrial door linked to Alzheimer's, cancer
Using CRISPR interference screening, scientists at the Whitehead Institute have uncovered the gene that serves as a doorway to the mitochondrial membrane, providing a molecular basis for understanding its role in cancer and Alzheimer's disease Read More
CDMO Lonza continues drive to support cell and gene therapy commercial customers
In an interview with Science Advisory Board, Alberto Santagostino, senior vice president and head of cell and gene technologies at Swiss contract development and manufacturing organization (CDMO) Lonza, discussed bluebird bio's two recent U.S. Food and Drug Administration-approved gene therapies. Read More
Researchers develop way to observe bacteria in 3D environments such as tissues
Hydrogels have enabled Princeton University researchers to see how bacteria grow in 3D environments, enabling them to make unprecedented observations of bacterial colonies in their natural 3D state. Read More
GenNext wins $250K grand prize at 2022 BioTools Innovator capstone event
GenNext Technologies, a growth-stage company that enables analysis of protein higher order structure to improve and accelerate drug discovery development, won a $250,000 grand prize at the 2022 BioTools Innovator capstone event on October 13 in Carlsbad, CA. Read More
Bacterium promotes pancreatic cancer growth, adding to evidence of role of tumor microbiome
Virginia Tech researchers have discovered that infection with a bacterium causes pancreatic cells to release cytokines that promote solid tumor growth, potentially helping to guide future therapeutic interventions for cancer treatment. Read More
Cell and gene therapy sector is in midst of an ‘industrial revolution’: Miguel Forte
Science Advisory Board spoke with Dr. Miguel Forte, CEO of Bone Therapeutics and president-elect of the International Society for Cell & Gene Therapy, at last week’s 2022 Cell & Gene Meeting on the Mesa about the state of the cell and gene therapy sector. Read More
Antibodies hit drug-resistant cancer cells to improve durability of targeted therapies
Scientists at the Perlmutter Cancer Center at New York University Langone Health have created antibodies designed to target and kill cells that develop resistance to targeted therapies, thereby tackling a barrier to durable anticancer effects. Read More
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