This method is changing what we know about hypoxia in cancer and inflammation

May 7, 2020 -- This method is changing what we know about hypoxia in cancer and inflammation

This method is changing what we know about hypoxia in cancer and inflammation Millipore – Preparation, Separation, Filtration & Monitoring Products Web version

Millipore - Preparation, Separation, Filtration & Monitoring Products

When O2 is scarce, this happens.

Real-time tracking of live cells gives new insights into hypoxia

A common characteristic of solid tumors, hypoxia creates resistance to apoptosis and to chemotherapy, enabling metastasis and aggressive malignant phenotypes that lead to poor clinical outcomes.

Read this technical article to find out how our CellASIC ® system for live cell imaging enables pathophysiologically relevant models for the study of apoptosis and hypoxic conditions, with video data as oxygen is withdrawn from cells.


Get Hypoxia App Note

The CellASIC® system for live cell imaging uses:

Microfluidics plates to allow control of gas, media, and temperature
A low-profile manifold and controller that fits next to your microscope
Optical-bottom plates to deliver publication-quality images and video

Our application note includes a protocol explaining how to automate hypoxic conditions, and uses a live-cell fluorescent indicator to quantify the impact of hypoxia on cell death, autophagy, and compound response in diverse cancer cell lines.

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