When O2 is scarce, this happens.
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Real-time tracking of live cells gives new insights into hypoxia
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Cancer cells are known to escape apoptosis,
by which a cell activates its own death in
response to stimuli. A common characteristic
of solid tumors, hypoxia creates resistance to
apoptosis and to chemotherapy, enabling
metastasis and aggressive malignant phenotypes.
Read this technical article to find out how our CellASIC® system for live cell imaging enables pathophysiologically relevant models for the study of apoptosis and hypoxic conditions, with video data as oxygen is withdrawn from cells.
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The CellASIC® system for live cell imaging uses - Microfluidics plates to allow control of gas, media, and temperature
- A low-profile manifold and controller that fits next to your microscope
- Optical-bottom plates to deliver publication-quality images and video
The CellASIC®
system makes it possible to automate hypoxic and apoptotic conditions, even for studying tough-to-capture non-adherent cell types like lymphocytes using the ingenious CellASIC® trap plates for mammalian cells.
Learn more about how the CellASIC® system incorporates advanced microfluidics technology to enable more predictive cell cultures, including mixed cultures, 3D and 4D cultures.
Our live cell imaging reagents for markers of apoptosis, hypoxia and other cellular conditions make getting more relevant data easy with this powerful, user-friendly system.
Best regards,
Your MilliporeSigma Team
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The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada.
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MilliporeSigma, the vibrant M and Millipore are trademarks of Merck KGaA, Darmstadt, Germany or its affiliates. All other trademarks are the property of their respective owners. Detailed information on trademarks is available via publicly accessible resources.
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