Scientists map gene expression without microscopes
A new framework called Tomographer, which uses sequencing data from tissues cut into thin strips in a way that allows them to be reconstructed, has been developed to spatially resolve gene expression data without the need for a microscope. The work was published in Nature Biotechnology on April 19. Read More
New algorithm helps integrate single-cell data from around the globe
A new algorithm enables researchers from around the globe to integrate multiple single-cell datasets from a variety of omics platforms in a quick and efficient process that can be done on standard computers. The technology, described in an April 19 Nature Biotechnology article, will help speed collaborative cell cataloging projects, such as the Human Body Map and Human Cell Atlas. Read More
Variant-resistant COVID-19 vaccines could be effective, cheap to make
Researchers have collaborated to create a new COVID-19 vaccine platform containing antigens against the fusion protein of the SARS-CoV-2 virus that could be effective against variants of the virus. The research was published online on April 15 in the Proceedings of the National Academy of Sciences. Read More
How can women overcome challenges to success in life sciences?
The gender gap is still alive and well in the life sciences, despite the great progress that has been made in recent years. But women can overcome challenges and find success in the life sciences industry, according to Olga Kubassova, PhD, chief executive officer of Image Analysis Group. Read More
AACR 2021: A case study of T-cell modulation for cancer immunotherapies
During a plenary session at the American Association for Cancer Research (AACR) 2021 virtual meeting held April 9-14, speakers described impressive work that researchers have done to modify and target T cells as a means of treating cancers. Read More
AACR 2021: How machine learning and artificial intelligence are transforming cancer research
The use of digital tools has been incorporated into many areas of cancer research. However, experts agree that machine learning and artificial intelligence are poised to transform drug discovery efforts even further in the near future. Several scientists discussed case studies of how machine learning can be used in cancer biology and drug discovery efforts during the virtual American Association for Cancer Research (AACR) 2021 meeting. Read More
AACR 2021: Single-cell technologies bring new insights to tumor cells
Single-cell technologies have become important tools for cancer researchers and provide scientists with the ability to make measurements of individual cells to unveil heterogenicity among tissues. Recent developments in single-cell research have been a focus of the virtual American Association for Cancer Research (AACR) 2021 meeting held online April 9-14. Read More
A CRISPR on-off switch for genes controls expression without altering DNA
A new gene silencing tool allows scientists to switch genes on and off without altering genetic sequences. The tool, described in a paper published in Cell on April 9, uses a modified CRISPR-Cas9 system to introduce reversible epigenetic changes that control gene expression. Read More
BioTools Innovator seeks to boost startups developing life science tools
BioTools Innovator is calling for applications to its inaugural competition to advance innovation by accelerating the growth of startups developing life science tools. Kathryn Zavala, PhD, managing director, recently discussed the program with ScienceBoard.net. Read More
NIH details progress of SCGE consortium
The U.S. National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) consortium has provided a detailed update, published in Nature on April 8, of projects to develop safer and more effective genome editing methods in somatic cells. Read More
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