July 20, 2022 -- In a paper published today in the journal Nature, scientists from Amgen subsidiary Decode Genetics with collaborators from Denmark report they have determined the whole-genome sequences of 150,119 individuals from the U.K. Biobank and identified more than 600 million sequence variants.
Data from the July 20 study are available to qualified researchers at the U.K. biobank research analysis platform. Single‐nucleotide polymorphisms (SNPs) and insertion and deletion (indel) variants frequency data are available at decaf.decode.com allowing for the identification of clinically important sequence variants.
It is the first report from what is being highlighted as the largest whole-genome sequencing effort to date. Scientists from Decode Genetics and the Wellcome Trust Sanger Institute plan to sequence 500,000 whole genomes in three years.
"Data of this type and quantity are going to revolutionize our ability to identify and characterize intergenic sequences of importance to human diversity, be it to the risk of disease and response to treatment or some other attributes," said Dr. Kári Stefánsson, founder of Decode Genetics and one of the authors of the paper, in a statement.
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