Moderna to use Roche tests in COVID-19 vaccine trials

By The Science Advisory Board staff writers

December 9, 2020 -- Moderna will use Roche's Elecsys anti-SARS-CoV-2 S antibody test in its messenger RNA (mRNA)-1273 vaccine research trials. The test can quantitatively measure the level of antibodies against SARS-CoV-2 in vaccine trial participants.

The companies believe that the test could help to establish a correlation between vaccinations and protection from COVID-19. Moderna's vaccine triggers an antibody response specifically to the anti-receptor binding domain of the SARS-CoV-2 spike protein. Ultimately, the correlation could help Moderna assess if, or when, revaccination would be necessary.


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