MilliporeSigma awarded U.S. patent for new CRISPR technology

By The Science Advisory Board staff writers

MilliporeSigma announced that the U.S. Patent and Trademark Office has granted the company's patent for CRISPR-chrom technology. This award is the second CRISPR patent granted to the company in the U.S. and its 23rd CRISPR-related patent worldwide.

This places MilliporeSigma as the only provider with a patent for the fusion of chromatin-modulating peptides to CRISPR proteins. The ability to fuse chromatin, which often blocks DNA, with CRISPR-chrom technology improves efficiency of the gene-editing process, according to the company. The initial work on the technology was published in the CRISPR Journal in late February.

MilliporeSigma's full CRISPR patent portfolio includes CRISPR-related technologies covering foundational intellectual property and alternative genome-editing methods.


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