ImmunoGenesis data to be presented at SITC 2021

By The Science Advisory Board staff writers

November 3, 2021 -- Data from ImmunoGenesis will be presented at the Society for Immunotherapy of Cancer (SITC) annual meeting scheduled for November 10-14 in Washington, DC.

The following research titles will be presented:

  • "Human PD-L2 Triggers a Unique T Cell Inhibitory Program Through PD-1 Engagement Distinct Dual-Specific Antibodies Blocking Both PD-L1 and PD-L2 Engagement of PD-1 Restore Anti-Tumor Immunity"
  • "High-Potency Synthetic STING Agonists Rewire the Myeloid Stroma in the Tumor Microenvironment to Amplify Immune Checkpoint Blockade Efficacy in Refractory Pancreatic Ductal Adenocarcinoma"

  • "Intratumoral Delivery of High Potency STING Agonists Modulates the Immunosuppressive Myeloid Compartment and Induces Curative Responses in Checkpoint-Refractory Glioblastoma Models"
  • "Disrupted Oxygen Supply and Tumor Hyper-Oxygen Consumption Contribute Independently to Prostate Cancer Immune Privilege"
  • "Hypoxia Reduction in Tandem With Anti-Angiogenic Therapy Remodels the PDAC Microenvironment and Potentiates CD40 Agonist Therapy"

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