How to address challenges in producing AAV vectors
There are challenges in producing sufficient quantities of gene therapy products, particularly when it comes to adeno-associated virus (AAV) vectors, contends Ines do Carmo Gil-Goncalves, PhD, head of vector production for Cevec Pharmaceuticals GmbH. Gil-Goncalves discussed how Cevec’s Elevecta platform can help overcome these challenges at the American Society of Gene & Cell Therapy 2022 annual meeting. Read More
Omega Therapeutics looks to tap 'nature's operating system' to control gene expression
Precision genomic medicine company Omega Therapeutics is looking to harness “nature’s operating system” for controlling gene expression and cell differentiation, according to Thomas McCauley, PhD, chief scientific officer. McCauley spoke with ScienceBoard.net at the American Society of Gene & Cell Therapy annual meeting in Washington, DC. Read More
Delivery of gene therapies remains a key challenge
Gene therapy holds great promise for treating inherited disorders, cancers, and other diseases, but delivery of these therapies remains a key challenge, contends Kevin Foust, PhD, senior vice president for preclinical and translational medicine at Jaguar Gene Therapy. Foust spoke with ScienceBoard.net at the American Society of Gene & Cell Therapy annual meeting in Washington, DC. Read More
Next evolution of CAR T-cell therapy is solid tumors
While chimeric antigen receptor (CAR) T-cell therapy has become a game changer for some patients with blood cancer, the next area of evolution for the technology is solid tumors, said Sangamo CEO Sandy Macrae, PhD, at the American Society of Gene & Cell Therapy 2022 annual meeting in Washington, DC. Read More
Forge Biologics assembles scientific and manufacturing advisory board
Forge Biologics has created its new Scientific and Manufacturing Advisory Board filled with leaders in the field of gene therapy development and manufacturing. This independent panel represents Forge’s commitment to enhancing its gene therapy offerings through insights from experts in the field. Read More
Precision BioSciences presents preclinical data for gene editing therapies
Precision BioSciences is scheduled to display preclinical data for its Arcus-based gene editing studies at the American Society of Gene & Cell Therapy’s annual meeting in Washington, DC. The showcase will include two oral presentations and two posters highlighting gene editing study results. Read More
Sample management, characterization is a growing challenge in CGT
From academic research centers to small biotechs to large pharmaceutical companies, the numbers of biosamples and measurements are growing exponentially in the field of cell and gene therapy (CGT). Andrea O'Hara and David Lewandowski of Azenta Life Sciences, spoke with ScienceBoard.net at the International Society for Cell & Gene Therapy (ISCT) 2022 annual meeting about the challenge of sample management and characterization. Read More
Autologous cell therapy has its limitations, risks
Cell-based therapies generated using a patient's own cells, called autologous cell therapy, have their own inherent risks and limitations, contends Roman Vincent, senior global director of strategic marketing at MaxCyte. Vincent spoke with ScienceBoard.net at the International Society for Cell & Gene Therapy 2022 annual meeting in San Francisco. Read More
What's needed for cell and gene therapies to become the new standard of care?
Cell and gene therapies (CGTs) have the potential to be the new standard of care. Delara Motlagh, PhD, general manager at Terumo Blood and Cell Technologies, told ScienceBoard.net at the International Society for Cell & Gene Therapy 2022 annual meeting that increasing access to CGTs is critical to making that a reality. Read More
Automation, standardization hold potential for overcoming CGT manufacturing challenges
Challenges in cell and gene therapy (CGT) manufacturing can be overcome by fully automating and standardizing the process, contends David Smith, vice president of technical operations at Ori Biotech. Smith spoke with ScienceBoard.net at the International Society for Cell & Gene Therapy 2022 annual meeting about Ori Biotech's new digital platform that closes, automates, and standardizes CGT manufacturing. Read More
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