Single DNA strand cuts achieve safety and efficacy edge over CRISPR-Cas9 in fruit flies
CRISPR-Cas9 variants known as “nickases” that target a single DNA strand may increase the success rate of gene editing and reduce the risk of off-target mutations, according to a paper published in the journal Science Advances. Read More
Ga. researchers combine DNA barcoding, target sequencing
Researchers in Georgia have developed a system to make preclinical nanoparticle studies more predictive that combines DNA barcoding with a multiomic nanoparticle delivery system called single-cell nanoparticle targeting-sequencing. Read More
Tokyo team challenges 10x Genomics with new single-cell RNA sequencing method
Researchers have developed a single-cell RNA sequencing method that is designed to tackle the cell sampling bias of existing techniques and deliver high-precision data, according to a paper published on June 27 in Nature’s Communications Biology journal. Read More
Agilent launches new quadrupole mass spectrometers with built-in instrument intelligence
Agilent Technologies has announced new liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry quadrupole mass spectrometers that the company says will raise the level of built-in instrument intelligence and offer a higher level of instrument diagnostics to maximize system uptime for customers. Read More
Cancer researchers publish study on avidity enhancement of CAR T cells
A team of cancer researchers led by Dr. Marcela Maus have published a preclinical study detailing the use of the Lumicks z-Movi Cell Avidity Analyzer to provide more nuanced development of cancer treatments. The study focused on using Lumicks’ technology to identify chimeric antigen receptor (CAR) T cells that are best suited to treat acute myeloid leukemia. Read More
Forge Biologics assembles scientific and manufacturing advisory board
Forge Biologics has created its new Scientific and Manufacturing Advisory Board filled with leaders in the field of gene therapy development and manufacturing. This independent panel represents Forge’s commitment to enhancing its gene therapy offerings through insights from experts in the field. Read More
BD releases new reagents for enhanced flow cytometry data resolution
Becton Dickinson (BD) has launched a set of novel reagents, known as BD Horizon RealYellow and RealBlue Reagents, created with specialized dye technology and artificial intelligence guidance to improve flow cytometry insights. Read More
Mission Bio appoints new chief medical officer
Life sciences company Mission Bio has announced the appointment of Dr. Todd Druley, PhD, as chief medical officer, a newly created role at Mission Bio. Read More
Cellular map of tissues created by combining sequencing techniques
Researchers have described an approach to combine single-cell sequencing experiments with spatial transcriptomics to create maps of tissues according to cell type, according to new research published on March 21 in the journal Nature Biotechnology. Read More
Mission Bio announces its 1st single-cell Tapestri Center of Excellence
Mission Bio has announced its first Center of Excellence, located at Memorial Sloan Kettering Cancer Center (MSK). As the first single-cell Tapestri Center of Excellence for solid tumor research, the lab will drive academic and industrial best practices using single-cell DNA profiling to observe tumor heterogeneity and clonal architecture in solid cancers. Read More
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