FibroGen, HiFiBiO partner on 3 therapies

By The Science Advisory Board staff writers

June 18, 2021 -- FibroGen and HiFiBiO Therapeutics announced a partnership covering three HiFiBiO programs in immuno-oncology and autoimmune therapy.

Through the partnership, FibroGen will make a $25 million upfront payment to HiFiBiO, as well as payments upon option exercise. HiFiBiO may also receive up to a total of an additional $1.1 billion in future milestone payments across all three programs. HiFiBiO will also be eligible to receive royalties based upon worldwide net sales.

FibroGen exclusively licensed all products in the Galectin-9 program and will have sole right to develop them worldwide. The lead product candidate in the Galectin-9 program is expected to enter clinical development in the first quarter of 2023.

FibroGen has also obtained exclusive options to license all product candidates in HiFiBiO's CXCR5 and CCR8 programs. Each option may be independently exercised following delivery of program-specific data to be generated by HiFiBiO. If an option is exercised, FibroGen will have the sole right to develop products from that program worldwide.

The lead product candidates from the CXCR5 and CCR8 programs are expected to enter clinical development by the mid-2023, company leaders said.

HiFiBiO advances trial of SARS-CoV-2 neutralizing antibodies
HiFiBiO Therapeutics has completed the first cohort of a phase I clinical study evaluating a SARS-CoV-2 neutralizing antibody.
HiFiBio, ABL Bio to develop SARS-CoV-2 antibody
HiFiBio Therapeutics has partnered with South Korea-based ABL Bio to advance HFB30132A, a SARS-CoV-2 neutralizing antibody for the treatment of COVID-19...
HiFiBio submits IND for SARS-CoV-2 treatment
HiFiBio Therapeutics has submitted an investigational new drug (IND) application with the U.S. Food and Drug Administration for novel SARS-CoV-2 neutralizing...
HiFiBio partners with CoVIC for SARS-CoV-2 antibody therapies
HiFiBio Therapeutics and the Coronavirus Immunotherapy Consortium (CoVIC) will collaborate to develop SARS-CoV-2-neutralizing antibodies with potential...

Copyright © 2021

CPhI North America
August 10-12
Philadelphia, Pennsylvania United States
Bioprocessing Summit
August 16-19
Boston, Massachusetts United States
6th Annual CAR-TCR Summit
August 30 - September 2
European Congress of Immunology (ECI) 2021
September 1-4
Belgrade Serbia
Medical Affairs Strategic Summit (MASS)
September 13-15
New Brunswick, New Jersey United States
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter