ImmunoPrecise identifies SARS-CoV-2 neutralizing antibodies

By The Science Advisory Board staff writers

June 29, 2020 -- ImmunoPrecise Antibodies has identified several lead candidate antibodies with high neutralizing activity in vitro that are being manufactured for further testing and possible inclusion in the company's PolyTope monoclonal antibody therapy against COVID-19.

The selected lead antibodies are the result of functional screening of over 300 antibodies analyzed from human and llama cells utilizing proprietary phage display technology. These antibodies support the company's goal of generating a multitarget therapy that retains efficacy, even as SARS-CoV-2 continues to evolve.

The company is preparing to test the lead antibodies against additional mutated strains of the virus with preclinical studies slotted to begin this summer.

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