Scientists unlock the secrets of gut coil development
September 26, 2022 -- Scientists now have a better understanding of embryo gut development: They've learned the counterclockwise gut rotation that occurs when the organ is formed is orchestrated by two waves of the transcription factor Pitx2 Read More
NIH announces $600M in awards to launch next phase of BRAIN Initiative
September 23, 2022 -- The National Institutes of Health (NIH) has announced more than $600 million in additional funding for its Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative, which is aimed at revolutionizing the understanding of the human brain. Read More
Epigenetic treatment improves spinal cord regeneration in mice after severe injury
September 20, 2022 -- Weekly treatments with an epigenetic activator resulted in the regrowth of sensory and motor neurons in the spinal cord when given to mice 12 weeks after severe injury, according to a study published September 20 in the journal PLOS Biology. Read More
Enzyme from endangered bird linked to promising new therapies
September 19, 2022 -- Rice University researchers have discovered a rare enzyme that can be used to metabolically engineer cells to produce drugs, including thrombin inhibitors that break up blood clots. A bioinformatic survey found the key in the endangered crested ibis, a large white-plumaged wading bird. Read More
Scientists pinpoint why alveolar macrophages don’t develop properly
September 19, 2022 -- Researchers in Germany have solved the mystery of what prevents alveolar macrophages from developing properly: the transcription factor CCAAT/enhancer binding protein beta (C/EBPβ). Read More
Data science, computational biology find same ‘rules’ have shaped organelles
September 16, 2022 -- An international team of researchers, led by Norway’s University of Bergen, has used data science and computational biology to show that the same “rules” have shaped how organelles -- both mitochondria and chloroplasts -- have evolved. Read More
Qiagen, Neuron23 partner to develop companion diagnostic for Parkinson’s drug
September 15, 2022 -- Diagnostics company Qiagen and early-stage biotechnology company Neuron23 announced a master collaboration agreement to develop a companion diagnostic for Neuron23’s brain penetrant leucine-rich repeat kinase inhibitor to treat Parkinson's disease. Read More
Federal funding of $2B to support biotechnology and biomanufacturing
September 14, 2022 -- The White House announced on Wednesday federal funding of more than $2 billion to advance President Joe Biden’s executive order intended to enable the U.S. to harness the full potential of biotechnology and biomanufacturing. Read More
NIH researchers develop gene therapy for rare pediatric disease that causes blindness
September 9, 2022 -- Using patient-derived retinal organoids, researchers from the National Institutes of Health (NIH) have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood. Read More
CHOP spots genetic variants, gene pairings involved in type 2 diabetes
September 8, 2022 -- Children's Hospital of Philadelphia (CHOP) researchers used 3D mapping at a microscopic level to identify genetic variants and corresponding target gene pairings in the pancreas that are involved in type 2 diabetes. Read More
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