Cell culture, mouse studies offer potential new targets for cancer treatments
August 30, 2022 -- University of Gothenburg scientists have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice, potentially enabling future development of new drugs targeted at a range of cancers. Read More
University of Chicago, Kansas awarded $1.2M to transform understanding of RNA splicing
August 29, 2022 -- The W.M. Keck Foundation has awarded a $1.2 million grant to researchers at the University of Chicago and the University of Kansas to help identify human gene sequences that will respond to drug therapies. Read More
Bio-Rad offers antievolocumab antibodies for preclinical, clinical drug development
August 25, 2022 -- Bio-Rad Laboratories is now offering a range of antievolocumab antibodies approved for in vitro research purposes and for commercial in vitro testing services to support preclinical and clinical drug development. Read More
Animal studies provide new insights into mechanisms behind Crohn’s disease
August 22, 2022 -- Researchers, led by Massachusetts General Hospital, have found that inhibitors of an enzyme called Speckled Protein 140 can reverse intestinal abnormalities in mice with inflammation characteristic of Crohn's disease. Read More
High type of collagen equals higher metastasis
August 11, 2022 -- High levels of collagen type XII can make tumors more aggressive and trigger metastasis, according to research from the Garvan Institute of Medical Research in Australia. Read More
Molecule inhibits drug-resistant bacteria in mice with pneumonia, UTIs
August 10, 2022 -- A new molecule that inhibits drug-resistant bacteria in laboratory experiments, as well as in mice with pneumonia and urinary tract infections (UTIs), has potential for treating stubborn infections in humans, according to researchers. Read More
Ohio researchers safely harness the power of carbenes
August 8, 2022 -- Researchers from The Ohio State University have unveiled a new, safer method to turn carbenes into more stable molecules, which has implications for drug manufacturing. Read More
New drug heals nervous system damage from stroke
August 1, 2022 -- A new drug can repair nervous system damage caused by a stroke, at least in animal studies. In a preclinical study, researchers from the University of Cincinnati and Case Western Reserve University have found that one drug resulted in significant improvement in motor function, sensory function, spatial learning, and memory. Read More
Scientists safely add fluorine to drugs
July 28, 2022 -- An international team of scientists have found how to add the fluorine atom to macrolide antibiotics, which means not only changes in the final product’s structure, but also the ability to kill bacteria and work safely in patients. Read More
Genes explain the effects of psychedelic drugs
July 28, 2022 -- Not everyone has the same response to psychedelic drugs and North Carolina researchers have figured out why -- seven genetic variants of one serotonin receptor greatly impact a certain serotonin receptor’s structure and function. Read More
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