Phase Genomics introduces method to discover new viruses

By The Science Advisory Board staff writers

June 16, 2021 -- Phase Genomics has released its new ProxiMeta metagenome deconvolution platform to help researchers identify new phages and their bacterial targets in complex environments.

The computational method leverages Phase Genomics' proprietary proximity-ligation technology based on high-throughput chromosome conformation capture. The method can capture physical genetic linkages inside bacterial cells and identifies DNA sequences that reside within the same organism, specifically in the context of the microbiome.

The technology allows for the discovery and reconstruction of new viral and bacterial genomes, according to the firm. The technology can also measure the host range of newly discovered viruses.

The new platform will aid phage therapy development and infectious disease research. The method and several datasets demonstrating the platform's capabilities were recently published on bioRxiv.

NovoBiome launches to develop microbiome-based therapies
NovoBiome has been launched as a drug discovery company focused on the development of live biotherapeutic products targeting the microbiome-gut-liver...
CRISPR phage offers precision medicine tool to fight bacterial infections
In an attempt to combat bacterial infections, Locus Biosciences is developing bacteriophage therapies that deliver CRISPR-Cas3 machinery directly to specific,...
Galmed, MyBiotics collaborate on microbiome-based treatments
Galmed Pharmaceuticals and MyBiotics Pharma have entered into a research and development collaboration agreement to advance microbiome-based treatments...
Enterome begins trial for microbiome-based immunotherapy
Clinical-stage biopharmaceutical company Enterome has begun its first clinical trial for E02401, a microbiome-based cancer immunotherapy candidate.

Copyright © 2021

Cell Bio 2021
December 11-15
San Diego, California United States
Antibody Engineering and Therapeutics
December 13-17
San Diego, California United States
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter