Lyell and Pact partner on T-cell therapy

By The Science Advisory Board staff writers

June 18, 2020 -- Lyell Immunopharma and Pact Pharma have formed a strategic partnership to jointly develop and test a next-generation personalized anticancer T-cell therapy against solid tumors.

The companies will develop personalized T-cell therapy using the patient's own T cells through nonviral precision genome engineering for tumor neoantigen specificity. This therapy aims to overcome potential tumor resistance and T-cell exhaustion.

Pact will receive upfront and milestone payments from the partnership. If successful, the drug development program will be jointly owned and each company will share profits equally.

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