Precision NanoSystems launches T-cell kits for mRNA-lipid nanoparticles

By The Science Advisory Board staff writers

April 21, 2021 -- Precision NanoSystems has launched its GenVoy-ILM T Cell Kit for messenger RNA (mRNA) to enable lipid nanoparticle-based ex vivo gene transfer.

The kit allows scientists to use mRNA-lipid nanoparticles to generate high yields of engineered primary human T cells in a simple workflow. The GenVoy-ILM T-cell kit uses lipid nanoparticles designed to exploit endogenous uptake pathways to deliver mRNA into activated human primary T cells to mediate titratable, uniform expression levels with high cell viability, according to the company.

The mRNA-lipid nanoparticles are compatible with established T-cell culture media, allowing for rapid integration into existing workflows. The kit can be used for the development of T-cell therapies.

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