Taysha establishes additional collaboration for minigene payloads

By The Science Advisory Board staff writers

March 9, 2021 -- Taysha Gene Therapies has established a multiyear collaboration with a team of Yale University researchers. The goal is to advance next-generation minigene payloads for adeno-associated viral (AAV) gene therapies for the treatment of neurodevelopmental disorders.

This collaboration follows the company's previously announced collaborations with the Cleveland Clinic and University of Texas Southwestern Gene Therapy Program (UTSW) to support the creation of a novel next-generation minigene platform designed to overcome key challenges in gene therapy.

The current collaboration is with Dr. Yong-Hui Jiang, PhD, professor and chief of medical genetics at Yale University. The team of Yale University researchers will create minigene payloads to treat neurodevelopmental disorders, including intellectual disability. Also, UTSW will produce viral vector constructs that incorporate the minigene payloads and evaluate the constructs for in vivo and in vitro efficacy.

As part of the collaboration, Taysha will have an exclusive option on new payloads, constructs, and intellectual property associated with, and arising from, the research conducted under the agreement.

Taysha collaborates on minigene payloads for AAV gene therapy
Taysha Gene Therapies has established multiyear collaborations with the Cleveland Clinic and the University of Texas Southwestern Gene Therapy Program...
Taysha, UTSW start fund to speed up CNS gene therapies
Taysha Gene Therapies and the University of Texas Southwestern Medical Center (UTSW) have launched a fund to accelerate the development of adeno-associated...
AllStripes, Taysha Gene Therapies partner on rare disease gene therapy program
AllStripes and Taysha Gene Therapies have entered a multiyear collaboration focused on advancing the development of TSHA-104, an adeno-associated virus...

Copyright © 2021 scienceboard.net

Cell & Gene Meeting on the Mesa
October 11-13
Carlsbad, California United States
IDWeek 2022
October 19-23
District of Columbia United States
American Society of Human Genetics Annual Meeting
October 25-29
Los Angeles, California United States
International Society for Pharmaceutical Engineering Annual Meeting
October 30 - November 2
Orlando, Florida United States
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter