CRISPR edited rat embryos reveal cause of rare pediatric neurodegenerative disease Using CRISPR gene editing technology on rat embryos, University of Wisconsin-Madison researchers have revealed the mutation that is responsible for progressive gait abnormalities and other symptoms in human infants and young children with a rare neurodegenerative disease.Read More
Combination therapy improves survival in mice with deadly glioblastoma Combining an antidepressant and vascular endothelial growth factor inhibitor improves outcomes in mouse models of a hard-to-treat type of brain cancer, despite neither treatment being efficacious as a single agent, according to new research.Read More
Imaging technique reveals previously unseen nanostructures in brain tissue Swellable hydrogels have enabled researchers to “decrowd” biomolecular structures in cells and tissues, revealing previously hidden nanostructures and providing imaging of the structure of Alzheimer’s-linked amyloid beta plaques in greater detail than has been possible before.Read More
Boosting neuron production offers viable treatment strategy for Alzheimer’s: mice study A new study from University of Illinois Chicago researchers shows that boosting neurogenesis, the process by which new neurons are formed in the brain, increases the number of newly formed neurons involved in storing and retrieving memories in the hippocampus of mice with Alzheimer’s disease.Read More