AACR 2021: Single-cell technologies bring new insights to tumor cells Single-cell technologies have become important tools for cancer researchers and provide scientists with the ability to make measurements of individual cells to unveil heterogenicity among tissues. Recent developments in single-cell research have been a focus of the virtual American Association for Cancer Research (AACR) 2021 meeting held online April 9-14.Read More
A CRISPR on-off switch for genes controls expression without altering DNA A new gene silencing tool allows scientists to switch genes on and off without altering genetic sequences. The tool, described in a paper published in Cell on April 9, uses a modified CRISPR-Cas9 system to introduce reversible epigenetic changes that control gene expression.Read More
Mirum licenses two PFIC gene therapies from Vivet Mirum Pharmaceuticals has obtained exclusive worldwide rights to develop and commercialize two proprietary adeno-associated virus gene therapy programs from Vivet Therapeutics for progressive familial intrahepatic cholestasis (PFIC).Read More
BioTools Innovator seeks to boost startups developing life science tools BioTools Innovator is calling for applications to its inaugural competition to advance innovation by accelerating the growth of startups developing life science tools. Kathryn Zavala, PhD, managing director, recently discussed the program with ScienceBoard.net.Read More
Oncolytic virus shows therapeutic promise against skin cancer Coxsackievirus combined with immunotherapy appears safe and effective against advanced skin cancer in patients who are unable to have their tumors surgically removed, according to a study to be presented at the American Association for Cancer Research 2021 annual meeting.Read More
Deargen optimizes prediction of candidate drug structures Artificial intelligence drug discovery and development company Deargen is touting results of its controlled molecular generator technology that overcomes limitations associated with existing models of predicting molecule properties.Read More