Cytovia, Cellectis expand partnership to boost collaboration in China

By The Science Advisory Board staff writers

November 22, 2021 -- Cytovia Therapeutics and Cellectis have expanded their partnership on transcription activatorlike effector nuclease (TALEN) gene-edited iNK (NK cells derived from induced pluripotent stem cells, or iPSC) to allow for a broader collaboration in China.

Cellectis will continue its development of a new TALEN, which Cytovia uses to edit iPSCs, according to the two firms. The collaboration now includes a new chimeric antigen receptor target, which will be developed in China by CytoLynx Therapeutics, Cytovia's joint venture.

Cellectis will receive $20 million in Cytovia stock in addition to $805 million in development, regulatory, and sales milestones plus royalties, the two firms said.

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