NovoBiome launches to develop microbiome-based therapies

By The Science Advisory Board staff writers

May 4, 2021 -- NovoBiome has been launched as a drug discovery company focused on the development of live biotherapeutic products targeting the microbiome-gut-liver axis.

The company is building ex vivo research and discovery platforms, leveraging expertise in microbiology and artificial intelligence, to analyze the symbiotic relationship between the microbiota and the human intestine. NovoSift is designed to mimic human intestinal physiology and unlock new insights into disease pathophysiology and reveal novel drug targets, compounds, and live biotherapeutic drug candidates.

NovoBiome's first drug candidate, ADC-001, for nonalcoholic fatty liver disease and nonalcoholic steato-hepatitis, is made of an anti-inflammatory bacterium with demonstrated in vitro and preclinical potency. The company aims to begin human clinical trials by 2022-2023.

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