Biochemistry
Bacterial structures are critical to the development of new antibiotics
A research team from Cornell University have uncovered a unique regulatory mechanism unique to bacterial that may provide crucial insight for antibiotic targeting of pathogens. The work was published in Nature Structural & Molecular Biology on November 18.  Discuss
Researchers use drug repurposing to identify new treatment for Metabolic Syndrome
A research team from the University of Trento find a novel method for using old drugs in new ways, specifically for Metabolic Syndrome. This revolutionary technique, published on November 18 in Nature Communications, uses a systems biology approach to investigate deregulated biological processes and identify drug repurposing candidates.  Discuss
New mechanism elucidated for essential molecule-sorting organelle
A new study published in Nature Communications on November 15 suggests a new mechanism by which vesicles are transported out of the Golgi apparatus for the formation and maintenance of endosomes. The work, conducted by researchers from Tokyo University of Science and the Institute of Science and Technology in Austria, changes the paradigm of how materials are sorted and distributed once they enter cells.  Discuss
Single-molecule resolution technique allows researchers to quantify secondary transport
St. Jude researchers from Columbia University and New York State Psychiatric Institute present new evidence about the mechanics of how secondary active transporter proteins function. This report is published in Nature on November 13.  Discuss
Novel mitochondrial phenomenon helps explains early neurodegeneration
Northwestern University Feinberg School of Medicine scientists discovered a novel pathway that leads to neurodegeneration in amyotrophic lateral sclerosis (ALS). The study was published in Frontiers in Cellular Neuroscience on November 7. The pathway could explain the development of early stages of neurodegeneration which affects voluntary muscle movement such as walking and talking.  Discuss
New nanoparticles help reduce inflammatory disease
Researchers from Washington State University have discovered a potential new treatment option for diseases associated with inflammation. The study, published in Science Advances on November 6, describes a new patent-pending nanotechnology that specifically targets activated neutrophils that compromise the immune system.  Discuss
Novel enzyme structure discovered by scientists
A research team at the University of California, Riverside, has discovered the structure of a novel RNA-modifying enzyme and identified the mechanism that controls substrate specificity. The study was published in Nature Communications on November 6 and explains how protein machinery in cells is regulated to target RNA molecules for modification.
Novel strategy for studying mitoribosomal and mitochondrial impact on disease
Researchers from the Karolinska Institutet in Sweden have developed a new experimental tool for studying mitochondrial protein synthesis in vivo. This research is presented in the October 5 issue of Cell Reports.  Discuss
Researchers identify microproteins with major implications in disease
A new study published in Nature Communications on October 25 provides evidence of how microproteins contribute to cellular stress. Researchers from Salk Institute suggest that these small proteins can cause dysregulation, which underlies several debilitating diseases including cancer, neurodegenerative disorders, and diabetes.  Discuss
New study provides molecular insight into how memory changes with age
Researchers from King's College London and The Open University add evidence as to why memory in old age is less flexible than in young adulthood. They published research on October 17, in Current Biology.  Discuss
Conferences
11th Annual PEGS Europe
November 18-22
Lisbon Portugal
Antibody Engineering & Therapeutics
December 9-13
San Diego, California United States
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30, 2020
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30, 2020
London, Greater London United Kingdom
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Conferences
11th Annual PEGS Europe
November 18-22
Lisbon Portugal
Antibody Engineering & Therapeutics
December 9-13
San Diego, California United States
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
American Society for Microbiology (ASM) Biothreats
January 28-30, 2020
Arlington, Virginia United States
Festival of Genomics 2020
January 29-30, 2020
London, Greater London United Kingdom
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