Biochemistry
COVID-19 shuts down research labs as concern grows among scientists
Almost half of all scientific research labs that participated in a recent survey were shut down due to concerns about the COVID-19 outbreak. Survey results indicate that scientists are quite concerned and that their work is considerably impacted by the pandemic, according to a new COVID-19 scientist sentiment tracker.  Discuss
Extracellular RNA identifies new Alzheimer's biomarker
The association of extracellular RNA with upregulation of the phosphoglycerate dehydrogenase gene may be a useful presymptomatic biomarker for Alzheimer's disease, according to an article published in Current Biology on March 26.  Discuss
Researchers reveal vulnerabilities of 'addicted' cancer cells
New findings about the mechanism by which some cancer cells can become "addicted" to glucose could lead to fresh approaches to targeted cancer therapies. The results of the research were published in Nature Cell Biology on March 30.  Discuss
Scientists use bioinformatics to investigate origin of SARS-CoV-2
While many scientists urgently work toward developing successful therapies to fight the COVID-19 pandemic, some are looking in the opposite direction: to where SARS-CoV-2 came from. A new report published in the Journal of Proteome Research suggests that while bats are a likely natural reservoir, an intermediate host is probable.  Discuss
Scientists alter cell function with genetic engineering, polymer science
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools.  Discuss
Systems-based analysis helps researchers understand cell migration
An international team of researchers has developed a unique library to study the regulation of the cytoskeleton in space and time. The work, published in Nature Cell Biology on March 23, takes a systems-based approach to gain an overview of this process.  Discuss
Could more sugar-based drugs be on the way?
Researchers from Denmark have developed a new technique to characterize complex sugar molecules in exquisite detail never before achieved, according to a report published on March 20 in Nature Communications. They hope to leverage the new structural information for the development of therapies.  Discuss
Cryo-EM sheds light on ion channel regulation
A long-standing hypothesis about the regulation of ion channels has been confirmed by cryoelectron microscopy (cryo-EM) imaging. The research presented in Nature on March 18 advances the basic understanding of key cellular processes that can be leveraged for a number of therapeutic and research applications.  Discuss
Researchers make sweet music with protein design technique
What does protein design have to do with music theory? A group of researchers from Massachusetts Institute of Technology saw commonalities between the two and designed a technique based on sonification that translates protein structures into musical scores as part of their effort to design new proteins. The details were published in APL Bioengineering on March 17.  Discuss
New biocompatible microparticles created with heat, light
A new simple and scalable protein-processing technique based on temperature-sensitive phase changes creates unique microarchitectures within microparticles for use in drug delivery and other bioengineering applications, according to a study published in Nature Communications on March 12.  Discuss
Conferences
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April 28 - May 1
Amsterdam, Noord-Holland Netherlands
Lab of the Future USA
May 19-20
Boston, Massachusetts United States
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International
September 21-24
Boston, Massachusetts United States
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Conferences
BioProcess International Europe
April 28 - May 1
Amsterdam, Noord-Holland Netherlands
Lab of the Future USA
May 19-20
Boston, Massachusetts United States
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International
September 21-24
Boston, Massachusetts United States
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