Neuroscience

New study provides molecular insight into how memory changes with age
Researchers from King's College London and The Open University add evidence as to why memory in old age is less flexible than in young adulthood. They published research on October 17, in Current Biology.  Discuss
Scientists build a better brain map
Researchers at Cold Spring Harbor Laboratory published a new study in Cell, on October 17, that introduces barcoded anatomy resolved by sequencing (BARseq), the next generation of MAPseq.  Discuss
Study shows that Huntington's disease can be slowed by modifying brain cells
A new study led by researchers at UCLA published in Science Translational Medicine on October 16 found that Huntington's disease (HD) damages astrocytes at the early stages of the disease, contributing to neuropsychiatric symptoms.  Discuss
Dementia-associated atrophy predicted by brain networks
A new study uses brain maps to predict how brain atrophy spreads in patients with frontotemporal dementia (FTD). The experiment, conducted by UC San Francisco scientists, adds to a growing body of data suggesting that brain cell loss associated with dementia spreads via synaptic connections between established brain networks.  Discuss
New molecular cause identified for neurodegeneration in Alzheimer's disease
A collaborative research effort uncovered evidence for a new molecular basis for neurodegeneration seen in patients with Alzheimer's disease. Researchers from Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital published the study in Cell Reports on October 8.  Discuss
Super-resolution imaging characterizes individual synaptic proteins
It is now possible to rapidly image synaptic proteins at high-resolution thanks to a new technique developed by researchers at MIT and the Broad Institute of Harvard. Details of the technique which use fluorescent nucleic acid probes to label different proteins are described the September 26 Nature Communications article.  Discuss
Repurposed drug shows potential to slow neurodegeneration in Parkinson's disease patients
Collaborative research from the University of Iowa and researchers in China and Spain, show evidence that a current drug used to treat prostate cancer may improve Parkinson's disease (PD) symptoms by slow neurodegeneration. The results from experimental models and clinical database analysis were published on September 16, in the Journal of Clinical Investigation.  Discuss
New drug target identified for common brain cancer
Research led by the Cleveland Clinic has identified a potential new therapy in the treatment of glioblastoma. An article published in Cancer Discovery on August 21, identifies FGF2 (fibroblast growth factor 2), as a novel drug target for glioblastoma, the most common primary malignant brain tumor.  Discuss
The Parkinson’s Foundation launches large-scale genetic study, aiming to improve patient care and speed clinical trials
More than 10 million people worldwide are currently living with Parkinson’s disease (PD), a neurodegenerative disorder that impacts the dopamine-producing neurons in the brain. Scientists do not know exactly what causes PD, but they believe it is a combination of genetic and environmental factors. Nearly 10% to 15% of all PD cases are caused by genetic mutations. A new study aims to understand how the disease develops and how it can be treated or cured. This study, PD GENEration: Mapping the Future of Parkinson’s Disease is currently being conducted by the Parkinson’s Foundation.  Discuss
Visualizing big data in the life sciences gets an upgrade with new software
A new software developed by researchers at the Max Delbrück Center for Molecular Medicine (MDC) uses algorithms to reconstruct and scale data acquired by light-sheet microscopy that renders a supercomputer unnecessary. Light microscopy techniques provide extremely detailed information but result in terabytes of data which is nearly impossible for scientists to process. MDC researchers are helping make sense of this data.  Discuss
Conferences
Virology, Emerging Diseases & Vaccines
October 21-22
Amsterdam Netherlands
10th CNS Summit
October 31 - November 3
Boca Raton, Florida United States
11th Annual PEGS Europe
November 18-22
Lisbon Portugal
Antibody Engineering & Therapeutics
December 9-13
San Diego, California United States
Society for Laboratory Automation and Screening (SLAS) 2020
January 25-29, 2020
San Diego, California United States
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