Ampio made the announcement following completion of the U.S. Food and Drug Administration review of the company's investigational new drug application for intravenous treatment with Ampion of COVID-19 patients. Now, the company is cleared to proceed with human trials.

Ampion is based on an immunomodulatory molecule derived from the N-terminus of human serum albumin. The drug has been shown to reduce inflammation by reducing pro-inflammatory cytokine production in T cells. Therefore, Ampion may be effective in interrupting the inflammatory cytokine storm associated with COVID-19 and improve patient outcomes, according to the firm.

Immunic begins phase II immunotherapy for COVID-19
Immunic has enrolled the first COVID-19 patients in a phase II clinical trial of IMU-838, a selective oral dihydroorotate dehydrogenase (DHODH) inhibitor.