10X Genomics launches FFPE Visium assay for research use

By The Science Advisory Board staff writers

June 10, 2021 -- 10X Genomics has launched its new Visium Spatial Gene Expression for formalin-fixed and paraffin-embedded (FFPE) assay, which gives researchers the ability to assess the whole transcriptome across an entire FFPE tissue sample.

FFPE processing is challenging because of the inherent damage caused to nucleic acids during fixation. The product, which was developed based on requests from customers performing translational research, addresses this challenge by using new chemistry developed for the company's Visium platform that allows for massive throughput and next-generation sequencing of clinical research samples.

Visium spatial gene expression for FFPE features:

  • Unbiased whole-transcriptome analysis
  • Full tissue section coverage that removes analysis boundaries associated with predefined regions of interest
  • High cellular resolution with 1 to 10 cells per spot depending on tissue type
  • Compatibility with histological analyses, allowing for morphological context overlaid with transcriptomic analysis
  • Ready-to-use assay kit, eliminating the need for specialized instrumentation

10X genomics is now shipping the Visium for FFPE assay kit, which contains all the reagents and consumables needed for whole-transcriptome analysis in human FFPE tissues sections.

Expression of triple-positive ductal carcinoma in situ (TPDCIS) markers compared to immunohistochemistry staining of TPDCIS.
Expression of triple-positive ductal carcinoma in situ (TPDCIS) markers compared to immunohistochemistry staining of TPDCIS. Image courtesy of 10X Genomics.
If you like this content, please share it with a colleague!
10x Genomics launches low-throughput gene expression kit
10x Genomics has launched its chromium single-cell gene expression low-throughput kit, a new offering designed to enable single cell analysis.
Competition within Single-Cell Analysis Technology
The excitement surrounding the ability to measure genomic, epigenomic, transcriptomic, and metabolic status in individual cells is reflected in the high...

Copyright © 2021 scienceboard.net


Conferences
CPhI North America
August 10-12
Philadelphia, Pennsylvania United States
Bioprocessing Summit
August 16-19
Boston, Massachusetts United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter