Charles River to provide clients with Valence AI tech

By The Science Advisory Board staff writers

April 6, 2021 -- Charles River Laboratories and Valence Discovery have formed a strategic partnership to provide clients with access to Valence's artificial intelligence (AI) platform for molecular property prediction, generative chemistry, and multiparameter optimization.

Valence's deep learning platform enables the design of small-molecule drug candidates in novel regions of chemistry, followed by rapid optimization against project-specific potency, selectivity, safety, and pharmacology criteria. The company's prediction tools work in areas where only small amounts of training data are available, thereby overcoming a critical limitation of existing machine-learning technologies in drug discovery.

The combination of Valence's machine-learning technologies with Charles River's end-to-end capabilities will accelerate discovery efforts from hit design through lead optimization, the companies said.

Through the collaboration, Charles River clients will have the option to access Valence's platform to support their drug discovery efforts. Clients can expect increased diversity in chemical matter being investigated, rapid optimization, and improved success rates for drug discovery projects.

Financial details of the partnership were not disclosed.

Charles River acquires Retrogenix for $48M
Charles River Laboratories has paid approximately $48 million U.S. to acquire the U.K.-based contract research organization Retrogenix.
Charles River to pay $875M to buy Cognate BioServices
Charles River Laboratories has signed a deal to pay about $875 million in cash to acquire cell and gene manufacturer Cognate BioServices.
Charles River, Cypre collaborate on in vitro services
Charles River Laboratories is joining forces with Cypre to advance the understanding of the tumor microenvironment and predict therapeutic efficacy. Charles...
How is the pharma-AI partnership landscape changing?
Artificial intelligence (AI) is taking on a growing role in drug discovery and development, with some 250 firms in a market space that's worth over $9 billion....
Charles River Laboratories acquires Distributed Bio
Charles River Laboratories has acquired Silicon Valley-based antibody drug discovery firm Distributed Bio for $83 million in cash.

Copyright © 2021

Register below for our weekly Letter from the Editor to receive the latest Science news and insights.
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter