Applied Biomath highlights presentations at SITC meeting
By The Science Advisory Board staff writersNovember 4, 2021
Company principal scientist David Flowers, PhD, will present a poster titled, "A Computational Semimechanistic Pharmacology Model of ATG-101, a PD-L1/4-1BB Bispecific Antibody for Treatment of Solid Tumors." The work describes the company's collaboration with Antengene on the development of a systems pharmacology model for understanding the treatment's tumor-killing mechanism.
A second poster presentation describes results of the company's collaboration with Genmab and is titled, "Dose Selection for DuoBody-PD-L1×4-1BB (GEN1046) Using a Semimechanistic Pharmacokinetics/Pharmacodynamics Model That Leverages Preclinical and Clinical Data."
The SITC meeting will be held November 10-14, 2021.