New 'antibody-decorated nanocrystals' target cancer cells
Researchers have bioengineered a metal-organic framework antibody drug delivery system that has the potential to fast-track personalized therapies for cancer and other diseases. The findings were published December 7 in the journal Advanced Materials. Read More
Bioengineered peptide combats antibiotic-resistant bacteria
Researchers have engineered a bioinspired molecule that was highly effective in clearing infections caused by antibiotic-resistant bacteria strains in a mouse model, according to a paper published in Scientific Reports on December 6. But there's a twist: The molecule doesn't act like an antibiotic. Read More
Aclaris Therapeutics publishes zunsemetinib preclinical research
Aclaris Therapeutics has published preclinical research of zunsemetinib in pancreatic cancer in the peer-reviewed journal Science Translational Medicine on December 1. Read More
Gamma delta T cells may hold key to malaria immunity
Scientists have shown how a poorly understood group of immune cells -- gamma delta T cells -- are directly involved in immunity to malaria, according to research published December 1 in Science Translational Medicine. The results promise to spur the future development of next-generation malaria vaccines. Read More
Decode Genetics publishes largest study of the plasma proteome
In a study published December 2 in Nature Genetics, scientists at Decode Genetics, a subsidiary of pharmaceutical company Amgen, demonstrated how measuring levels of several proteins in plasma at population scale combined with data on sequence diversity and RNA expression dramatically increases insights into human diseases and other phenotypes. Read More
New machine-learning approach promises to speed drug design
A new approach to machine learning outperformed current machine-learning methods in drug design, demonstrating its potential in speeding up the drug discovery process, according to research published online November 29 in the Proceedings of the National Academy of Sciences. Read More
BioTools Innovator opens 2022 applications
BioTools Innovator is now accepting applications from startups and emerging growth companies for its second annual accelerator program. The program aims to advance innovation in life science and improve human health by accelerating the growth of best-in-class startups that are developing and commercializing biotechnology products, platforms, and services. Read More
Machine-learning system decodes nuclear magnetic resonance spectra of organic crystals
A group of researchers has developed a machine-learning framework that assigns the chemical shifts of organic crystals directly from their 2D structure -- accelerating an often time-consuming process. The study was published November 26 in Science Advances. Read More
Sartorius grows operations in France
Sartorius is expanding its capacities for production, innovation, and storage in France by investing 100 million euros ($117 million) between 2021 and 2025. Read More
Istari moves quickly to validate its poliovirus vaccine-based cancer immunotherapy
It's been a busy year for Istari Oncology, which is developing its PVSRIPO viral immunotherapy based on the poliovirus vaccine. Istari's President and CEO Matt Stober and Chief Medical Officer Dr. Garrett Nichols recently spoke with ScienceBoard about the progress of PVSRIPO for the treatment of solid tumors. Read More
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