How one CDMO is navigating the global supply chain disruption


June 24, 2022 -- The COVID-19 pandemic has disrupted supply chains and production schedules around the world, forcing contract development and manufacturing organizations (CDMOs) to be proactive in meeting customer demands and tight timelines.

Based in Laupheim, Germany, Rentschler Biopharma prides itself on the contribution it makes to the global availability of biopharmaceuticals as a full-service CDMO and outsourcing partner for bioprocess development and current good manufacturing practice (cGMP).

Federico Pollano, Rentschler's senior vice president for business development, spoke with ScienceBoard.net at the 2022 Biotechnology Innovation Organization (BIO) International Convention about how the company is navigating the worldwide supply chain disruption.

Pollano said that over the last two years Rentschler has "strategically" sourced raw materials and media, while "working on different systems" including both disposable and stainless steel bioreactors. He noted that Rentschler pioneered single-use manufacturing and was among the first adopters of disposable bioreactors in the CDMO business.

However, Rentschler offers both disposable and stainless steel equipment. The company has stainless steel bioreactors up to 3,000L as well as 2,000L and 1,000L single-use bioreactors.

"You can balance [the options] also in stainless steel where you have less material demand," Pollano said. "It's very important to be flexible and also to be able to adapt your processes according to the available media, and on the other side also to have access to the inventories from the relevant vendors."

Watch the video below to learn more.



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